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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2b3fbbc3cadb36ed783608797573c0289b3ea64fc2c71cd5949171b0c215f7' 
  AND token = 'DO8Ks3d4CnG5g5d1A141XmgUHFKfkBnFpWVGFVQMnIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}