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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3137507cfab0c8eac87f8169c53349851f7966a0fa15be680827c0f415bdcd' 
  AND token = '+0Zgo5cTrlhyBQwH2vwMDaK0rBAPuk9l1boRAQLR7vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}