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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f4463f3c5e00bcb87fe42be4255383cfbb540dc00dd283ca855aa7ca26324c' 
  AND token = '2rqwg3CifZ+NNtsVzBjLfkYMhzYjnIIIzY/ioshFEuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}