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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1a0719f3a90abf2a6589808a85cbec278e0b273eaa7d5384a4649ebf3bff6a8' 
  AND token = 'jh1ygpVZLK8enOHXO9nWuh+2OKR2WMg8VOD8VjymYVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}