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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dffdd144f3187ca861b753de3da9f224c0db203c6b0faa5e50dd47c8b4f5de1' 
  AND token = 'h28TNU3Y205LjpA75/Gsf74Vi2ydLDpDX1zQv2kBkrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}