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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ddde866ac48dab217634d2728130c094d9f65c98c2fbcd7527ec81a77b5b0fc' 
  AND token = '6Xtxjkh75o2yU7sylTnlnzfsYXX09q1GRCmcM43V9LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}