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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e699dd39bf0ef37641b1ee9fd4f9b7c916e1a38d2598e86d006a35e59e972b15' 
  AND token = 'JhI4xCnGCwoQESG+tl7K/11yAMeNMI53AwxsIcd0m+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}