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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b141e37c784bc305c6c87c3ef44f1fc7f9abfe50d7071e102c0687e59f97b65b' 
  AND token = 'X+E16sUab3eac9M1oA4CvgM4HDmaZQGZzdq/cTwT9eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}