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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b13376a4ac7f75fed949f2e29e646f14033c069a7f6b773aae515eda4494f4fc' 
  AND token = 'RVPp/PpC/jPSM5wnSVVm6veN9eqSE71iJaftCC2/IV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}