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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c0c8a1fbd96e03665bcdae366cefc876c46fed144ae31ecac83b1e138f20840' 
  AND token = 'vIFJzHSDD7aTKypSoJt6kbtfyWWu8uEigh8c263quLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}