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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe3a4dc9800d63343609090a194dba1cbfe57b38325671a311ca644e3a12b707' 
  AND token = '/V/TNZYWsCJR+g4rCurf4TJVRZ8/lx3cJ++sihK51Tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}