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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7789e87cc15d025b7ce653347b076d7b341e94b73dbd8cb04428d3a1a2093054' 
  AND token = 'mA3Y4ZgZCusiM7NVP6b5N+VAjeUlL6gr+9bo2CZ2aRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}