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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8bb269451932828e79c047b6665ece5c0e3a12ad53fb3fe3a5bf2682acc13c' 
  AND token = 'FpopQA0AXDSCGXp1+aftItNCKP87k/2hzFCXUDPry8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}