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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4919ec7b6ed7e613503d8b7f37a7b19311448e7086cfb58f4bba6733368fb751' 
  AND token = 'mBHysRnaXsD3DWffXtKsYJ7+AZ7F9VC4I/5Cq1xX7Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}