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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63e16bb24e6e8b01d652a040c5c4ee18b863925391bc0dea293dba5fe5cbd738' 
  AND token = 'pZllJuFp/j/FtsQPE2qJ78bQjos3q7SjtJjKFv8h5tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}