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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad54290f4ce7290fa2c6a4216bdeac2a59ed702c2c55923d31f8867ccf335a0d' 
  AND token = '4dNsTuq7PX/N6ZcV7kNx1GsgCRhRiQd9GVgDsbQJj3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}