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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '113b3bb1d108ea1128f6ecdf35af58a0e65a9dff9168a071bbf7478a052650e1' 
  AND token = 'PuiD11nkadqCXF08wMungECd7cx727VcBcCrQtB/85Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}