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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d90e9a0af898f33cdc032bde347163e3f588c87fd6dfea3644cc0c2acea9fd' 
  AND token = 'CDWT/a4g/TgjL0y1t9a8UwXFfHon9z/Ow1HZSJDcgMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}