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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a675363eca2add703e01047c9730ce765fb7862ca8fbfed1162f15a0ab90d522' 
  AND token = '0ATZC+IKM/lswn+UGq+WlzH7Db6TJm6OEyU91Z1XxH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}