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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35bbd21382a37b9198320241d2750c70efe022cb0124b79cc1117dd373d7b9a5' 
  AND token = 'BnlPcYx0S6I4Uio4accl1b+jMNwOPfVanufY0V7VFjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}