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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'feb377f7bbe12d4d7d70ced3cf06b70736552fd858151691d7fc464fc2b7b177' 
  AND token = 'DdEf2xfyk4Uxazg7vySQK/N45bru9Jfoylgd1SIwdnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}