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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492f6e0c6c432516f12c903b43a64ca2b99c518da542fdd71165f0dd6b0b3382' 
  AND token = 'kadQwDy0/9KICJel+NVvk6m/pYIE5d9NLAtomZJYWgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}