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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726d734759c925a4daa3f5a8a70fb451ff9882fd2176d2841e7b42ed564141a9' 
  AND token = 'NMZb+e4RI66j5Y8jDe31KT7OOYRKrG2+ocU6BfsfZ9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}