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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5338cd4b3f5fcb33219657a38e6727eaa91b78f1b9a6a84c457d7c8e4fe98bf7' 
  AND token = 'cRw7dOg1bMzrICSk1A25ik/axrE7+nT18l1FG8g8Xdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}