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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df55033f6571fc5f0c9285a978f60a62c0b6034045ba56ffa7f20a1e09e28f0a' 
  AND token = 'M052QYNSTzP4GvhG+XoTU2VNI0nSJ8XGw0ieSQsTfqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}