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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2848193557a3c444efdea7a9f958708ef9811842cd3b5d65bd90427f5e91c9fe' 
  AND token = '6t5b+CQsGOmAWCkkUAE8xrN03uQHbqrqpGb5w26QUoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}