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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df7443d3ef08f36b066bb5cd240e95fc489c490b36805e50c4a2e67cac4edbd' 
  AND token = 'cbql3O+zQaH4uxO3G4Jk8ZJbkOt4mYyr07mknebsJwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}