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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8c810855359be9d184b5132ba2156dd46fd081e0da0d8d8af2e204b5fc7945a' 
  AND token = 'fMITrHjCyC8GJtIXIZTLXrQmqJ4vsrEiN7uLyubEgm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}