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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36f8ca46705e98f757176492d8ec5421ebdc80ec5c8b111541f699c1e119e282' 
  AND token = 'LF8vl2zBGbAWQ+7TIiioEvfg2AQ/OIh6VQgoIphLy2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}