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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d835dce1639621ba0bb3b910cacdc108a393ce1e666d4b40cd6ec4e09d371d6' 
  AND token = 'gsKfOfzZvTTYnzdaqZsw2te1miVekQPAyw/rQKvA0Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}