SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a034ee4f311da9506f43e5a53f3351a75d282d9e36c8c65b91b7fefe38078f' 
  AND token = 'MKEdO6fPY9eRzGNGjls/C/8N0wEEC93VoY3hKhMt3GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}