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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e60a25eced12754ccc1cc5f9e7caea17fcbb508ad98b9b7dd91a6566c10f89c' 
  AND token = 'GS/JmA7OnVHy7v3qOuS4A7IbMNNrCwTvzTUEX58cdcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}