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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0b2a8c6b928399b9db0b134ba288d65abaa5f8620a6be4b9e1d42de760c92e' 
  AND token = 'cUVp6FD6cibMMQI9bMfFYH9ru/QzzgNMTGYV8PAQSPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}