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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dcab0397e879a4e5535728ea6dfec55cbd6a00967c53a9cc9d44afef5fc794e' 
  AND token = 'LVU8872j6icr9dkQSW+GzCfYTaaNNW41TGpoxwUxTKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}