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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d250ea54fc15e8635a6ec5a2d568a6ab6a3445d0a5c0cdba776cd071bb3a7e' 
  AND token = 'cKXVT4HFdwB/FrpMLG8LjlD9qDpJhGaLZoOCYNLTtjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}