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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd37a89b08d8da637659fbba858f3547b8d5ed35dd846c80b3a4be054331878' 
  AND token = 'KQGHsKz6RkkAM9b0CcuuHmwhAd0o0ufYxaWHtv2tR0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}