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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6bc6619e684a6908e89ae38416431ddacc5442a3cc8aa636c625f5c31bbca57' 
  AND token = 'rINiDz+DRktImGQ0peo4CTVnQLX77KxhQ7V/VZ2QRC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}