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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b14d445e7f32ae0b5d952f9d0ab97dfe34acae1e9203ffc60da25e3bdf9bebc9' 
  AND token = 'tPLS43nv3IiMYnhXEb0pxC6h+rCjU0CzyEvrc0ECCPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}