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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e12df7da00694b0a7b854d4e00bc04c497b188e5f871cc683304768cf834d8' 
  AND token = '5nxaG6qWlUFUi+YGUNOdollL5b9xX+WofYeHjcyToh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}