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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25afd32e9ed9420abc44e1f08997061dbf7deb811b184d6bc3a7f6d81b617d3' 
  AND token = 'm4kWfQvv0UVeSl6m4wwOZmMO9yCFty+8OCFLoJSUp8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}