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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb58b9a444628e70bcb693329b442f4a72f83aee97ab71701cfeb8155c7a743' 
  AND token = 'kHfTT6LUjRVE3kYu+TrQkZLlvBYBJbWayB8hU4fc3tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}