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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aae3f1c9a9117ba0b67f1e9b8c367cb88ab34db148b4cfddb82cf32a8d366b33' 
  AND token = 'dr7wKi04LJyE4BR0eD5EP89ZMQUUzSlI1oV0qyLK3Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}