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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735813ffd4d95cc24adbf09ea579a02c5f1556a57959c385d262899a7ef94a08' 
  AND token = 'EAmMr5i2jZsC+HWz2cW1TAeWRj/HFpaTbPcyE2EtZ78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}