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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec757facd65900b6368cc049a1c4395327b6a36c012806654f35e1c2a50c15ea' 
  AND token = 'c87tSAZ2+vB0o6qSjokOtTIIG9CaW72Lat2LNbPW1SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}