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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '765c4c6be6faaad3c76576a64cad43713df81be5974c750420ce922b0e3aed4a' 
  AND token = 'K/91kr1v8C4ZE5FCS4upb4RMz1w3PdQ04VJOgLV4ZTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}