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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afe00ca33fe566fd10c9354ade2114b728ec93e5549f9829888d673cbf0d7528' 
  AND token = 'OMOMKQ8tuCxg+1a3vq+WGbZETjFu3bPeUad5Cglkh7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}