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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a80a5c9a71db9d18b6cd3420e0769a74307c7b47da9e1dff24648c30fd7807f' 
  AND token = 'QKZZVD5j2EZQAO6zF9LqOJzoccnpRb3sYXZAJlp2z1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}