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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '750fcbdec8a614f0fa85b731f7cee6f88f963fa17a6bd28919a2a52a0a946c21' 
  AND token = 'F3iq42lW+qmDYk1RhtF98HZEEUEYFctCGQ7dj/pGWcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}