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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea764e242a1928fe177e27b5b6e0eae1309b127067421e56e3aea8c8bfe99622' 
  AND token = 'uOa6qJ/xUwD+XBCu3FXiQWIi9dRImx4DHHHie2sMCnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}