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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e614f14a2c2a52ebbc0d05946c56236bf33001c528cd93e50d6c56ce67fee74' 
  AND token = 'rH6BHgJbH1WOD/Z1/zSSs2XENMqSdZ/UfI0x6Zl0zAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}